Smarter Pregnancy App Links Improved Lifestyle Habits to Lower Maternal Blood Pressure in Early Pregnancy

Researchers analyzed data from the Rotterdam Periconception Cohort between 2010 and 2019, including 132 pregnant women who used Smarter Pregnancy for 6-24 weeks in the intervention group and 1091 pregnant women in the control group.
Participants’ outcomes included changes in systolic, diastolic, and mean arterial BPs between baseline and first trimester measurements, with median gestational age of 7 weeks at inclusion.
Analysis tracked lifestyle behaviors in the intervention group at 12 and 24 weeks using risk scores for vegetables, fruits, smoking, and alcohol consumption.
Multivariable analysis adjusted for baseline BP measurements, age, gestational age, geographic origin, parity, and conception mode to evaluate program effectiveness.

The intervention group demonstrated significant reductions in systolic (β, −2.34 mmHg; 95% CI, −4.67 to −0.01; P = .049), diastolic (β, −2.00 mmHg; 95% CI, −3.57 to −0.45; P = .012), and mean arterial BP (β, −2.22 mmHg; 95% CI, −3.81 to −0.52; P = .011) compared with controls.
Among women who underwent assisted reproductive technology (ART), significant reductions were observed in diastolic (β, −2.38 mmHg; 95% CI, −4.20 to −0.56) and mean arterial BP (β, −2.63 mmHg; 95% CI, −4.61 to −0.56).
Program usage was associated with decreased lifestyle risk scores at 12 weeks (β, −0.84; 95% CI, −1.19 to −0.49) and 24 weeks (β, −1.07; 95% CI, −1.44 to −0.69), indicating improved lifestyle behaviors.
Lifestyle risk scores significantly decreased in both ART and natural pregnancy subgroups after program completion.

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