CARDIOPROGRESS
Foundation for the advancement of cardiology

Accelerated biological ageing and cardiovascular disease trajectories: a multistate analysis Accelerated biological ageing has been linked to elevated risks of hypertension (HTN) and cardiovascular diseases (CVDs), yet its role in shaping the dynamic progression from health to HTN, to CVDs, and ultimately to mortality remains poorly understood. In this regard, the data of 136,614 participants of the UK Biobank aged 38 to 73 years, who did not have hypertension and CVD at the initial stage, were analyzed.

Diagnostic performance of exercise stress testing findings and coronary microvascular dysfunction in patients with angina with non-obstructive coronary artery disease Coronary microvascular dysfunction (CMD) is common among patients with angina with non-obstructive coronary artery disease (ANOCA) and leads to poorer clinical outcomes. Exercise stress testing (EST) was shown to have a high specificity for detecting CMD. However, the relationship between diagnosing CMD using different invasive physiological parameters and thresholds and the association between EST findings and the endotype of CMD remains unknown.

Engineered blood clots stop bleeding in seconds The blood in the vascular system of the body supports vital functions, but when it leaves the body, it must quickly form a strong protective barrier — a clot that prevents death. However, because natural blood clots are known to form very slowly, heavy bleeding from accidents, battlefield injuries, and surgical complications leads to many potentially preventable deaths. In an article for the journal Nature, Jiang et al. They talked about the achievements of bioengineering that solve this problem by fundamentally changing the structure of blood clots.

Cardiac resynchronisation therapy among adults with a systemic right ventricle: a multicentre experience Researchers conducted an international retrospective study including patients over 18 years of age from 33 centers with transposition of the great arteries (TGA) after atrial switch surgery and congenitally corrected TGA.

Cardiovascular disease in Sickle cell: mechanisms, diagnostics and therapeutic advances Cardiovascular complications are increasingly recognized as a major cause of morbidity and early mortality in patients with sickle cell disease, yet they remain underdiagnosed and underestimated. In a new review, the authors summarize current knowledge on a wide range of cardiovascular manifestations, including myocardial dysfunction, pulmonary hypertension, cardiac iron overload, arrhythmia, myocardial infarction, stroke, and sudden death, with an emphasis on their unique pathophysiological mechanisms in Wolf-Hirschhorn syndrome.

Parsimonious machine learning model to predict 1-year mortality and procedural futility after transcatheter aortic valve replacement Current risk assessment scores are insufficiently accurate in predicting long-term mortality after transcatheter aortic valve replacement, limiting their usefulness for decision-making regarding the feasibility of the procedure. The researchers aimed to develop and test a machine learning model on external data using only preoperative variables to predict all-cause mortality within one year.

Congenital heart disease in England: a national cohort study from fetal diagnosis to end of infancy Population-based studies of congenital heart defects (CHDs) often include only children who have undergone cardiac surgery, leading to an underestimation of the number of cases that do not require intervention. In a new study, the authors analyzed the outcomes of all identified cases of structural CHDs in England from prenatal to one year of age.

Younger Age Offers No Protection From HFrEF Deaths Patients aged 40-85 years with heart failure with reduced ejection fraction (HFrEF) died at higher rates over 5 years than matched peers from the general population across all age groups; however, the greatest relative impact was seen in younger adults (aged 40-49 years).

Atopic Dermatitis in Childhood Not Linked to Early Cardiovascular Risk In a UK study of 9281 participants followed from childhood into early adulthood, atopic dermatitis, including more active and severe atopic dermatitis, was not consistently associated with cardiometabolic risk scores, traditional cardiovascular risk factors (blood pressure, lipid profiles), or measures of subclinical atherosclerosis.

Changes in Physical Activity Following Heart Failure in Humans and Animal Models: A Scoping Review According to a review, patients with heart failure (HF) experience decreased physical activity (PA) due to fatigue, shortness of breath, and psychological and environmental factors. This leads to a decline in physical function and prognosis, but the extent of the decline in PA specifically due to heart failure remains unclear.

New Tool to Guide Transcatheter Aortic Valve Replacement A new German trigger tool identified adverse events in pediatric cardiology admissions, with most events causing temporary harm. The tool demonstrated good interrater reliability and was feasible for systematic detection of patient harm in hospitalized children.

The release of a new open access journal of cardiology In August 2026, a group of cardiologists launched the peer—reviewed open access journal OpenSource: Cardiology. The main difference of the publication is the complete absence of publication fees for the authors.

New Pediatric CPR Guidelines: Key Updates for Clinicians More than 7,000 community-acquired cardiac arrests occur in the United States each year. New methods are aimed at restoring breathing, clearing clogged airways and improving survival.

Upcoming Joint Guidelines to Address Obesity Management Upcoming evidence-based clinical guidelines from three obesity organizations will address US-based pharmacologic management of overweight/obesity and its complications in adults.

Resistant hypertension: a new look Modern management of patients with arterial hypertension requires a consistent approach to treatment and prevention, with particular attention paid to the problem of low adherence to treatment. Lifestyle optimization and elimination of secondary hypertension causes are identified as key strategies.

Results of the 36th International Congress of Cardiology "Great Wall" and the Asian Congress of Cardiology 2025 The 36th International Congress of Cardiology “Great Wall” and the Asian Congress of Cardiology 2025 took place at the National Exhibition Center in Beijing from October 16 to 19, 2025.

New guidelines may help prevent sudden death in myocarditis The European Society of Cardiology (ESC) recently released its 2025 guidelines for the management of myocarditis, which also includes extensive discussion of pericarditis and the wide range of overlap between these types of cardiac inflammation. The guidelines were presented at the ESC Congress 2025 in Madrid and simultaneously published in the European Heart Journal.

Nobel Prize in Physiology or Medicine 2025 The Nobel Prize in Physiology or Medicine 2025 was awarded to Mary E. Brunkow, Fred Ramsdell and Shimon Sakaguchi "for their discoveries concerning peripheral immune tolerance.

World Heart day 2025 World Heart Day is celebrated annually on September 29. Since its inception, the Cardioprogress Foundation has actively collaborated with the World Heart Federation and, to celebrate this occasion, organizes events in various cities across the Russian Federation.

EASD to Feature Major Trial Results, Clinical Guidance The European Association for the Study of Diabetes (EASD) 2025 Annual Meeting will feature major clinical trial results in type 2 diabetes (T2D), type 1 diabetes (T1D), obesity, several new clinical practice guidelines, and much more.