CARDIOPROGRESS
Foundation for the advancement of cardiology

A Week of Anticoagulation Halves Post-PCI Radial Occlusion Rate BOSTON — Following transradial access for angiography or a percutaneous coronary intervention (PCI), a low dose of the factor Xa inhibitor rivaroxaban for 7 days reduces the risk of an access-site occlusion by 50%, according to results of the randomized RIVARAD trial.

Expert Consensus Guides Use of Cardiac CT in Patients With Cancer The Society of Cardiovascular Computed Tomography (SCCT) has issued an expert consensus statement to guide use of cardiac computed tomography (CCT) in the care of cardio-oncology patients.

Frailty Poses No Limit to HFpEF Meds BARCELONA — Increased frailty of patients with heart failure with preserved ejection fraction (HFpEF) should have no bearing on whether those patients receive sacubitril/valsartan (Entresto), according to results of a post hoc analysis of data from a pivotal trial.

PASCAL for MV Repair Noninferior to MitraClip in CLASP IID, FDA Took Notice A newly available transcatheter device for edge-to-edge mitral valve (MV) repair, named for a famed scientist-inventor, is similar to the long-available MitraClip (Abbott) for short-term efficacy and safety, suggests an interim but prespecified analysis from a randomized trial.

How Does Salt Intake Relate to Mortality? Intake of salt is a biological necessity, inextricably woven into physiologic systems. However, excessive salt intake is associated with high blood pressure. Hypertension is linked to increased cardiovascular morbidity and mortality, and it is estimated that excessive salt intake causes approximately 5 million deaths per year worldwide. Reducing salt intake lowers blood pressure, but processed foods contain "hidden" salt, which makes dietary control of salt difficult. This problem is compounded by growing inequalities in food systems, which present another hurdle to sustaining individual dietary control of salt intake.

Cumulative Blood Pressure Load: A Better Predictor of CV Events? Cumulative systolic blood pressure load, which can be calculated from serial blood pressure measurements, may provide better prediction of major cardiovascular events compared with traditional blood pressure measures, a new study suggests.

Vitamins or Cocoa: Which Preserves Cognition? Unexpected results from a phase 3 trial exploring the effect of multivitamins and cognition have now been published. Findings from a phase 3 study show daily multivitamin use, but not cocoa, is linked to a significantly slower rate of age-related cognitive decline.

Premature menopause is associated with increased risk of heart problems Menopause before 40 years of age is associated with elevated risks of heart failure and atrial fibrillation, according to a study published today in European Heart Journal, a journal of the European Society of Cardiology (ESC).

Social isolation, loneliness raise risk of death from heart attack or stroke by nearly a third Loneliness increases the risk of cardiovascular disease by almost a third, according to new research. Socially isolated individuals are about 30 percent more likely to suffer a stroke or heart attack — death from either. (San-Diego)

As Y Chromosomes Vanish With Age, Heart Risks May Grow It’s been known for more than half a century that many men lose their Y chromosomes as they age. But no one knew if it really mattered. The loss of Y could just be a sign of aging, like gray hair, with no clinical relevance. (Subscription required in order to read the article).

Climate change and health inequity a deadly mix for the most vulnerable: World Heart Federation Geneva, 29 September 2022 - On World Heart Day, the World Heart Federation (WHF) is calling for urgent action on climate change and health inequity, with millions more lives now at risk from cardiovascular disease, which is still the world’s biggest killer.

New ESC Guidelines for Cutting CV Risk in Noncardiac Surgery The European Society of Cardiology (ESC) guidelines on cardiovascular assessment and management of patients undergoing noncardiac surgery have seen extensive revision since the 2014 version. They still have the same aim — to prevent surgery-related bleeding complications, perioperative myocardial infarction/injury (PMI), stent thrombosis, acute heart failure, arrhythmias, pulmonary embolism, ischemic stroke, and cardiovascular (CV) death.

CONFERENCE NEWS

U.S. declares monkeypox public health emergency Following growing pressure to ramp up response efforts against monkeypox, the U.S. declared a public health emergency. There are around 6,600 infections nationwide, reaching all but two states. The White House plans to roll out several million doses of monkeypox vaccines and are targeting at-risk communities.

FDA Okays IN.PACT 018 Drug-Coated Balloon for PAD The US Food and Drug Administration has approved the IN.PACT 018 drug-coated balloon (DCB) for the treatment of peripheral arterial disease, Medtronic announced today.

World Heart Summit 2022 THE SUMMIT WILL CONVENE WORLD LEADERS IN CARDIOVASCULAR HEALTH IN THE HEART OF GLOBAL HEALTH DIPLOMACY, JUST AHEAD OF THE 75TH WORLD HEALTH ASSEMBLY. Now in its 7th edition, the World Heart Summit will take place on 21-22 May 2022, just two days ahead of the World Health Assembly, under the timely and universal theme of Cardiovascular Health for Everyone.

New ACC Guidance on Cardiovascular Consequences of COVID-19 The American College of Cardiology (ACC) has issued an expert consensus clinical guidance document for the evaluation and management of adults with key cardiovascular consequences of COVID-19. The document makes recommendations on how to evaluate and manage COVID-associated myocarditis and long COVID and gives advice on resumption of exercise following COVID-19 infection.

THE CONTRIBUTION OF SOVIET HEALTHCARE WORKERS TO THE VICTORY IN THE SECOND WORLD WAR It is difficult to overestimate the contribution of healthcare workers to the Victory in the Second World War. The losses in the war could have been more devastating if not for the courage of people were fighting for the lives of the wounded and sick on the battlefields. Over 200,000 doctors and a half-million army of paramedics worked at the front and in the rear.

Lowering BP According to Newest Guidance Would Cut CV Events Using the 2021 Kidney Disease: Improving Global Outcomes (KDIGO) guideline target of systolic blood pressure (BP) < 120 mm Hg, 66% of adults with chronic kidney disease (CKD) would be eligible for BP lowering, according to a study from South Korea.

Distress-Related Metabolite Levels Predicts Future Cardiovascular Events A metabolite-based distress score derived from measurements of molecular biomarkers in women related to chronic distress can predict future risk for cardiovascular disease. The study covered in this summary was published in medRxiv.org as a preprint and has not yet been peer reviewed.