In situ assembly of an injectable cardiac stimulator
Without intervention, cardiac arrhythmias pose a risk of fatality. However, timely intervention can be challenging in environments where transporting a large, heavy defibrillator is impractical, or emergency surgery to implant cardiac stimulation devices is not feasible. Here, we introduce an injectable cardiac stimulator, a syringe loaded with a nanoparticle solution comprising a conductive polymer and a monomer that, upon injection, forms a conductive structure around the heart for cardiac stimulation.
Polycystic Ovary Syndrome: A Hidden Risk for Metabolic and Cardiovascular Diseases?
Women with polycystic ovary syndrome (PCOS) face an increased risk for type 2 diabetes (T2D), metabolic dysfunction–associated steatotic liver disease (MASLD), and cardiovascular disease (CVD), although these risks vary depending on PCOS phenotype.
Can Electronic Decision Support Improve Acute Heart Failure Care in EDs?
An electronic decision support tool may increase the prescription of guideline–directed medical therapy for patients with acute heart failure (AHF) in emergency departments (EDs), with no serious adverse events (SAEs) within 30 days among very low-risk patients who are discharged.
Evaluation of the World Health Organization-HEARTS hypertension control package in Bangladesh: a quasi-experimental trial
The World Health Organization (WHO) promotes the HEARTS technical package for improving hypertension control worldwide, but its effectiveness has not been rigorously evaluated.
Common Eye Disorder May Be Linked to Maternal Hypertension
Children whose mothers have a hypertensive disorder in pregnancy (HDP) may have an increased risk for strabismus, including exophoria and intermittent exotropia, new research shows. Preeclampsia and poorly controlled blood pressure may confer the greatest risk.
PET Imaging Finds Vulnerable Plaques That Cause MI
A new technique that can locate vulnerable coronary plaques at risk of rupturing and causing a myocardial infarction (MI) could help identify patients at high cardiovascular risk who might need more intensive treatment.
New Insight Into CVD, Stroke Risk in Migraine
Researchers are unraveling the complex relationship between cardiovascular (CV)- and stroke-related outcomes in migraine with, and without, aura.
How to Get Published in a Specialized Journal
Every month, hundreds of manuscripts land in the inboxes of biomedical journals. For example, researchers submitted more than 2200 articles to JAMA Cardiology in 2023. Only 6% of all original research papers were accepted.
Roche Blood Test for Lp(a) Designated Breakthrough Device
A blood test that measures lipoprotein(a) [Lp(a)] has received breakthrough device designation from the US Food and Drug Administration. The Tina-quant Lp(a) RxDx assay, developed by Roche in partnership with Amgen, is designed to identify adults with elevated Lp(a) levels who may benefit from lipid-lowering therapies currently in development.
New TAVI Platform Adds More Valve Sizes to Choose From
Intermediate valve sizes are at least as safe and effective as the standard sizes now available for transcatheter aortic valve implantation (TAVI), according to an international randomized trial.